蛛网膜下腔出血后神经元死亡机制的研究进展

doi:10.3870/j.issn.1672-8009.2026.01.012

摘要/Abstract

摘要： 蛛网膜下腔出血是一种神经系统的急危重症。蛛网膜下腔出血后引发的脑损伤机制复杂多样,其中神经元的死亡是关键环节。文章综述了近年来关于蛛网膜下腔出血后神经元死亡机制的研究,涵盖了神经元的凋亡、焦亡、自噬、坏死性凋亡及铁死亡等多个方面,并初步探讨了相关干预措施,旨在为蛛网膜下腔出血的临床治疗提供新的思路。

关键词: 蛛网膜下腔出血, 神经元死亡, 机制

Abstract: Subarachnoid hemorrhage(SAH)is a critical neurological emergency.The mechanisms of brain injury following SAH are complex and multifaceted,with neuronal death serving as a pivotal pathological process.This article reviews recent researches on neuronal death mechanisms following SAH,covering apoptosis,pyroptosis,autophagy,necroptosis,ferroptosis,and other pathways.It also preliminarily explores relevant intervention strategies,aiming to provide new insights for the clinical management of SAH.

Key words: subarachnoid hemorrhage, neuronal death, mechanisms

中图分类号:

R743.35

王海, 孙新刚. 蛛网膜下腔出血后神经元死亡机制的研究进展[J]. 医学分子生物学杂志, 2026, 23(1): 85-89.

WANG Hai, SUN Xingang. Advances in Mechanisms of Neuronal Death After Subarachnoid Hemorrhage[J]. Journal of Medical Molecular Biology, 2026, 23(1): 85-89.

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