动脉粥样硬化中内皮间充质转化的研究进展

doi:10.3870/j.issn.1672-8009.2022.03.015

医学分子生物学杂志 ›› 2022, Vol. 19 ›› Issue (3): 261-264.doi: 10.3870/j.issn.1672-8009.2022.03.015

动脉粥样硬化中内皮间充质转化的研究进展

华中科技大学同济医学院附属协和医院心脏大血管外科武汉市, 430000

出版日期:2022-05-31 发布日期:2022-06-20

Research Progress on Roles of Endothelial-mesenchymal Transformation in Atherosclerosi

Department of Cardiac Surgery, Union Hospital Affiliated to Tongji Medical College, Huazhong University of Science and Technology, Wuhan, 430000, China

Online:2022-05-31 Published:2022-06-20

摘要/Abstract

摘要： 内皮细胞是心脏、血管、淋巴管等器官组织的重要组成部分, 在心血管系统生理过程中起至关重要作用。内皮间充质转化 (endothelial-mesenchymal transition, EndMT) 调控内皮细胞向间充质细胞转化, 其参与动脉粥样硬化过程。 EndMT 可能为动脉粥样硬化的防治提供新靶点与思路。

关键词: 内皮间充质转化, 动脉粥样硬化

Abstract: Endothelial cells are important components of the heart, blood vessels and lymph vessels. They play a crucial role in regulating the physiological processes of the cardiovascular system. Endothelial-mesenchymal transition (EndMT) is the transition of endothelial cells to mesenchymal cells, and it has been reported to be involved in atherosclerosis. Various cytokines are changed during the process of EndMT. The study of EndMT may provide insight for the mechanism and treatment of atherosclerosis.

Key words: endothelial-mesenchymal transition, atherosclerosis

中图分类号:

田睿, 蒋晨, 陈新忠. 动脉粥样硬化中内皮间充质转化的研究进展 [J]. 医学分子生物学杂志, 2022, 19(3): 261-264.

TIAN Rui, JIANG Chen, CHEN Xinzhong. Research Progress on Roles of Endothelial-mesenchymal Transformation in Atherosclerosi[J]. Journal of Medical Molecular Biology, 2022, 19(3): 261-264.

动脉粥样硬化中内皮间充质转化的研究进展

Research Progress on Roles of Endothelial-mesenchymal Transformation in Atherosclerosi

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