医学分子生物学杂志 ›› 2022, Vol. 19 ›› Issue (4): 349-352.doi: 10.3870/j.issn.1672-8009.2022.04.014

• 综述 • 上一篇    

Adropin 蛋白在多囊卵巢综合征中的研究进展及临床意义 

  

  1. 山西医科大学附属人民医院生殖医学科 太原市, 030001 
  • 出版日期:2022-07-31 发布日期:2022-08-17

Research Progress and Clinical Significance of Adropin Protein in Polycystic Ovary Syndrome

  1. Department of Reproduction Medicine, the Affiliated People’s Hospital of Shanxi Medical University, Taiyuan, 030001, China
  • Online:2022-07-31 Published:2022-08-17

摘要: 多囊卵巢综合征 (polycystic ovary syndrome, PCOS) 是一种在育龄期女性中常见的疾病, 它的主 要临床表现是月经紊乱、 不孕、 痤疮、 多毛等症状, 可能伴随有糖脂代谢异常。 Adropin 是新近发现的一种 分泌性蛋白, 已证实其在调节糖脂代谢、 改善胰岛素抵抗中发挥着作用, 但具体作用机制及其临床意义尚 未完全明确。 文章简要综述 Adropin 蛋白的作用机理及其在多囊卵巢综合征中的研究进展及临床意义。 

关键词: Adropin 蛋白, 多囊卵巢综合征, 糖代谢, 胰岛素抵抗

Abstract: Polycystic ovary syndrome (PCOS) is a common disease in women of childbearing age. Its main clinical manifestations are menstrual disorders, infertility, acne, hirsutism, etc. , and may be accompanied by abnormal glucose and lipid metabolism. Adropin is a newly discovered secretory protein, which has been proved to be effective in regulating glucose and lipid metabolism and improving insulin resistance. However, its underlying mechanism in PCOS and its clinical significance are not fully understood. In this paper, we briefly reviewed the mechanism of adropin on regulating PCOS, and the research progress and clinical significance of adropin in PCOS.

Key words: Adropin, polyeystic ovary syndrome, glycometabolism, insulin resistance

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