Journal of Medical Molecular Biology ›› 2022, Vol. 19 ›› Issue (3): 261-264.doi: 10.3870/j.issn.1672-8009.2022.03.015

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Research Progress on Roles of Endothelial-mesenchymal Transformation in Atherosclerosi

  

  1. Department of Cardiac Surgery, Union Hospital Affiliated to Tongji Medical College, Huazhong University of Science and Technology, Wuhan, 430000, China
  • Online:2022-05-31 Published:2022-06-20

Abstract: Endothelial cells are important components of the heart, blood vessels and lymph vessels. They play a crucial role in regulating the physiological processes of the cardiovascular system. Endothelial-mesenchymal transition (EndMT) is the transition of endothelial cells to mesenchymal cells, and it has been reported to be involved in atherosclerosis. Various cytokines are changed during the process of EndMT. The study of EndMT may provide insight for the mechanism and treatment of atherosclerosis. 

Key words: endothelial-mesenchymal transition, atherosclerosis

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