Abstract: In recent years, the incidence of candidiasis has increased significantly due to the COVID-19 pandemic. Candida albicans infection and resistance of commonly used therapeutic drugs have become increasingly serious public health problems globally. The extract of Scutellaria baicalensis, its monomer components and the traditional Chinese medicine compounds preparations have been proved to have good anti- Candida albicans activities in experiments and clinics. However, themechanisms seem to be very complex, which may be related to inhibiting adhesion and invasion, affecting biofilm formation, inducing apoptosis, disrupting calcium homeostasis, disrupting glycolysis, inhibiting effecting pump, fighting inflammation and improving immunity.

Key words: Candida albicans , ,  , Scutellaria baicalensis,  , baicalein, baicalin