Journal of Medical Molecular Biology ›› 2024, Vol. 21 ›› Issue (2): 176-181.doi: 10.3870/j.issn.1672-8009.2024.02.014

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Research Progress on Glucocorticoids Induced Dysfunction of Trabecular Meshwork #br#

  

  1. Henan Provincial People’ s Hospital, Henan Eye Hospital, Zhengzhou University People’ s Hospital, Henan University People’ s Hospital, Zhengzhou, 450003, China
  • Online:2024-03-31 Published:2024-04-29

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Abstract: Glucocorticoids (GCs) could induce the morphological changes and dysfunction oftrabecular meshwork tissues. The changes in the trabecular meshwork tissues of the glucocorticoids ( GCs) induced glaucoma is similar with those of the primary open angle glaucoma ( POAG). However, the pathogenesis of POAG is still unclear, elucidating how GCs induce morphological changes of trabecular meshwork and the increase of aqueous humor outflow resistance is beneficial for exploring the pathogenesis of POAG. The effects of GCs on trabecular meshwork are summarized in this review.

Key words:

glucocorticoids, trabecular meshwork, glucocorticoid induced ocular hypertension, glaucoma


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