Abstract: MORC3 is an important member of the MORC nuclear protein superfamily. It is a genetic regulatory factor, which is often related to the occurrence of autoimmune diseases and cancer. In recent years, with the rapid development of molecular research technology, researches on the MORC3 molecular structure has also become a hot spot. Among them, the zinc finger structure and the ATP enzyme domain of MORC3 have attracted wide attention, and its immune regulatory effect has also been discovered. In addition, more and more studies have shown that MORC3 plays a diverse and irreplaceable role in the human body. This article mainly introduces the molecular structure and function of MORC3 and its role in regulation of genetic materials, and its participation in the development of diseases.

Key words: MORC3, CW domain, ATP enzyme domain, cancer, antiviral