Abstract: Primary glomerulonephritis is a group of common renal disease syndromes, whichcan deteriorate the quality of life of patients and increase the risk of renal disease progression. Long non-coding RNA (lncRNA) is a kind of non-coding regulatory RNA that can regulate a variety of cell biological processes. More and more reports have confirmed that lncRNA is closely related to the occurrence and development of primary nephrotic syndrome. Further researches on the relationship between lncRNA and primary glomerulonephritis are expected to lay a theoretical foundation for finding new biomarkers and therapeutic targets for primary glomerulonephritis.

Key words: long non-coding RNA, primary glomerulonephritis