Abstract: Polycystic ovary syndrome (PCOS) is a common disease in women of childbearing age. Its main clinical manifestations are menstrual disorders, infertility, acne, hirsutism, etc. , and may be accompanied by abnormal glucose and lipid metabolism. Adropin is a newly discovered secretory protein, which has been proved to be effective in regulating glucose and lipid metabolism and improving insulin resistance. However, its underlying mechanism in PCOS and its clinical significance are not fully understood. In this paper, we briefly reviewed the mechanism of adropin on regulating PCOS, and the research progress and clinical significance of adropin in PCOS.

Key words: Adropin, polyeystic ovary syndrome, glycometabolism, insulin resistance